10 Best over counter medications of 2025

Save up to 33% off

Best Choice

1

Claritin
Claritin Allergy Medicine for Adults, 24-Hour Non-Drowsy Loratadine 10mg Pills, Antihistamine, 100 Tablets
Main highlights

24-Hour Non-Drowsy Relief
Provides powerful, all-day allergy relief without causing drowsiness.

Ideal for Seasonal Allergies
Perfect for managing symptoms from pollen, dust, and pet allergens.

Highly Recommended for Spring
Praised for effectiveness during peak allergy seasons like Spring.
9.9

Exceptional

Our Rating

9.7
simple to consume

8.9
worth the money
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Value for Money

2

Excedrin
Excedrin Migraine Relief Caplets to Alleviate Migraine Symptoms - 200 Count
Main highlights

Triple Action Formula
Combines acetaminophen, aspirin, and caffeine for powerful migraine relief.

Ideal for Migraine Sufferers
Best for alleviating migraine symptoms like headache, light sensitivity, and nausea.

Quick Relief Praised by Users
Users appreciate its fast-acting relief, often within 20 minutes.
9.6

Exceptional

Our Rating

9.9
pain management

9.3
simple to consume

8.7
worth the money
3

Tylenol
Tylenol Extra Strength Acetaminophen Rapid Release Gels, Extra Strength Pain Reliever & Fever Reducer, Gelcaps with Laser-Drilled Holes, 500 mg Acetaminophen, 100 ct

24% Off
Main highlights

Fast Acting Relief
100-count Tylenol Extra Strength Rapid Release Gels work quickly to relieve pain and reduce fever with 500 mg acetaminophen.

Ideal for Adults and Teens
Suitable for adults and children 12 years and older, making it versatile for family use.

Highly Praised Effectiveness
Customers appreciate the fast action and effectiveness, noting the rapid relief and long-lasting results.
9.5

Excellent

Our Rating

9.7
simple to consume

9.5
worth the money

9.5
pain management
4

Amazon Basic Care
Amazon Basic Care Extra Strength Pain Relief, Acetaminophen Caplets, 500 mg, 1000 Count (Packaging may vary)
Main highlights

Effective Pain Relief and Fever Reduction
Contains 500 mg of Acetaminophen, comparable to Extra Strength Tylenol, for temporary relief from various minor aches and pains.

Versatile Use for Adults and Teens
Ideal for adults and children 12+ for pain relief and fever reduction due to colds, headaches, and more.

Cost-Effective Alternative to Brand Names
Praised for providing the same effectiveness as Tylenol at a lower price, making it a preferred choice for budget-conscious consumers.
9.2

Excellent

Our Rating

9.9
worth the money

9.7
simple to consume

9.7
pain management
5

Amazon Basic Care
Amazon Basic Care Nighttime Sleep Aid Tablets for Adults, Doxylamine Succinate 25 mg, 96 Count

28% Off
Main highlights

Effective Sleep Aid
Contains doxylamine succinate 25 mg to aid sleep.

Ideal for Nighttime Use
Best for adults needing help falling and staying asleep.

Rapid Sleep Induction
Praised for quick action and extended sleep duration.
9.0

Excellent

Our Rating

9.7
simple to consume

9.3
worth the money

8.2
quality of sleep
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6

Gas-X
Gas-X Maximum Strength Gas Relief Softgels with Simethicone 250 mg - 30 Count
Main highlights

Fast Relief with Simethicone 250 mg
Provides quick relief from gas and bloating with the highest dose of simethicone available in OTC products.

Ideal for Quick Gas Relief
Perfect for adults and children over 12 needing fast, effective relief from gas and bloating.

Highly Recommended for Easy Swallowing
Customers frequently praise the small, easy-to-swallow softgel design for convenient use.
8.8

Very Good

Our Rating

9.7
simple to consume

9.3
Flavor

8.7
worth the money
7

TUMS
TUMS Extra Strength Assorted Berries Antacid Tablets for Heartburn Relief, 96 count
Main highlights

Fast Relief with Extra Strength
TUMS provides quick relief from heartburn, acid indigestion, and sour stomach with 750 mg calcium carbonate.

Perfect for Multi-Symptom Heartburn
Ideal for burning chest, acid indigestion, sour and upset stomachs.

Delicious Assorted Berry Flavor
Customers love the berry flavor, making it enjoyable and effective.
8.5

Good

Our Rating
8

Motrin
Motrin IB Ibuprofen 200mg Tablets, Ibuprofen Pain & Fever Reliever for Headache, Backache, Muscular Aches, Menstrual Pain & Minor Arthritis Pain, Over-The-Counter NSAID Medicine, 225 ct

33% Off
Main highlights

Effective Pain Relief
Motrin IB tablets provide powerful relief from minor aches and pains.

Versatile Use Cases
Ideal for headaches, muscle aches, backaches, and menstrual cramps.

Customer Favorite Feature
Highly praised for its reliable and consistent pain relief.
8.3

Good

Our Rating

9.7
simple to consume

9.5
worth the money

9.5
pain management
9

Pepto Bismol
Pepto Bismol Chewable Tablets for Nausea, Heartburn, Indigestion, Upset Stomach, and Diarrhea - 5 Symptom Fast Relief, Original Flavor, 48 ct
Main highlights

Five Symptom Relief
Provides fast relief for nausea, heartburn, indigestion, upset stomach, and diarrhea.

Ideal for Travel
Perfect for on-the-go relief, making it travel-friendly.

Praised for Convenience
Customers appreciate its portability and ease of use.
8.2

Good

Our Rating

9.9
movability

9.7
Simple to use

9.3
simple to consume
10

Amazon Basic Care
Amazon Basic Care Loperamide Hydrochloride Tablets, 2 mg, Anti-Diarrheal, 24 Count (Pack of 1) (Packaging may vary)

23% Off
Main highlights

Key Features
Effective anti-diarrheal with 2 mg Loperamide HCl per tablet, gluten-free, capsule-shaped for easy intake. Comparable to Imodium A-D.

Ideal Use Cases
Optimal for controlling symptoms of diarrhea, including Travelers Diarrhea, suitable for adults and children over 6 years.

Customer Praise
Highly praised for its fast-acting relief of diarrhea, affordability, and comparable effectiveness to brand names.
8.1

Good

Our Rating

9.5
simple to consume

8.4
For traveling

8.4
Flavor

10 Best over counter medications of 2025

1

Claritin Allergy Medicine for Adults, 24-Hour Non-Drowsy Loratadine 10mg Pills, Antihistamine, 100 Tablets

9.7

8.9

2

Excedrin Migraine Relief Caplets to Alleviate Migraine Symptoms - 200 Count

9.9

9.3

8.7

3

Tylenol Extra Strength Acetaminophen Rapid Release Gels, Extra Strength Pain Reliever & Fever Reducer, Gelcaps with Laser-Drilled Holes, 500 mg Acetaminophen, 100 ct

9.7

9.5

9.5

4

Amazon Basic Care Extra Strength Pain Relief, Acetaminophen Caplets, 500 mg, 1000 Count (Packaging may vary)

9.9

9.7

9.7

5

Amazon Basic Care Nighttime Sleep Aid Tablets for Adults, Doxylamine Succinate 25 mg, 96 Count

9.7

9.3

8.2

6

Gas-X Maximum Strength Gas Relief Softgels with Simethicone 250 mg - 30 Count

9.7

9.3

8.7

7

TUMS Extra Strength Assorted Berries Antacid Tablets for Heartburn Relief, 96 count

8

Motrin IB Ibuprofen 200mg Tablets, Ibuprofen Pain & Fever Reliever for Headache, Backache, Muscular Aches, Menstrual Pain & Minor Arthritis Pain, Over-The-Counter NSAID Medicine, 225 ct

9.7

9.5

9.5

9

Pepto Bismol Chewable Tablets for Nausea, Heartburn, Indigestion, Upset Stomach, and Diarrhea - 5 Symptom Fast Relief, Original Flavor, 48 ct

9.9

9.7

9.3

10

Amazon Basic Care Loperamide Hydrochloride Tablets, 2 mg, Anti-Diarrheal, 24 Count (Pack of 1) (Packaging may vary)

9.5

8.4

8.4

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